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Treatment outcomes and safety of telitacicept in reducing proteinuria and hematuria for refractory childhood IgA vasculitis nephritis

Key takeaways

This report describes children with a hard-to-treat kidney inflammation (IgA vasculitis nephritis) who were given a drug called telitacicept. It appeared to lower protein and blood in the urine. This is a small, non-randomized report, so it shows promise, not proof.

Who did this work

Yue Xi (Beijing Children’s Hospital) · Nan Zhou (Beijing Children’s Hospital) · Qiang Sun (Beijing Children’s Hospital) · Chen Ling (Beijing Children’s Hospital) · Ying Liang (Beijing Children’s Hospital) · Lei Lei (Beijing Children’s Hospital) · Dan Wu (Beijing Children’s Hospital) · Zeping Cao (Beijing Children’s Hospital) · Xin Mo (Beijing Children’s Hospital) · Zhi Chen (Beijing Children’s Hospital)

Source

Indexed paper · OpenAlex — CKD concept sweep (DB seed + weekly delta) · 2026-08-08
https://doi.org/10.1186/s40001-026-04954-0