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Effect of semaglutide on kidney outcomes in the SELECT, FLOW, and SOUL trials: a prespecified pooled analysis.

Article A Peer reviewed Meta-analysis or large trial

Key takeaways

Researchers pooled three large trials (SELECT, FLOW, and SOUL) to look at how semaglutide affects the kidneys. The combined analysis showed the drug helped protect kidney function. Pulling together big trials makes this a strong finding.

Who did this work

Mann JFE · Badve SV · Baeres FMM · Belmar N · Brown-Frandsen K · Buse JB · Colhoun HM · Deanfield JE · Engelmann MDM · Hovingh GK · Idorn T · Lincoff AM

Source

Journal article · PubMed — the drug frontier · 2026 Aug 7
https://pubmed.ncbi.nlm.nih.gov/42567173/