← brief for 2026-08-11 · Slowing decline

Dapagliflozin preserves kidney function and reduces albuminuria in children with chronic kidney disease

Key takeaways

In children with chronic kidney disease, the diabetes drug dapagliflozin was linked to better kidney function and less protein leaking into the urine. Protein in the urine is a sign of kidney stress. This shows a link, not firm proof, and most study of this drug so far was done in adults. Larger trials in children are still needed.

Who did this work

Farahnak Assadi (Rush University Medical Center) · Elham Bidabadi (Guilan University of Medical Sciences) · Mojgan Mazaheri (Milad Hospital) · Fatemeh Ghane-Sharbaf (Mashhad University of Medical Sciences) · Toktam Faghihi (Tehran University of Medical Sciences) · Rama Naghshizadian (Kurdistan University of Medical Sciences) · Alireza Eskandarifar (Kurdistan University of Medical Sciences) · Anoush Azarfar (Mashhad University of Medical Sciences) · Simin Sadeghi-Bojd (Zahedan University of Medical Sciences) · Arash Abbasi (Children's Medical Center) · Behnaz Bazargani (Children's Medical Center) · Afshin Safaei-asl (Guilan University of Medical Sciences)

Source

Paper · OpenAlex, CKD concept sweep (DB seed + weekly delta) · 2026-08-06
https://doi.org/10.1093/ndt/gfag177