← brief for 2026-08-11 · Slowing decline

Safety and efficacy of glucagon like peptide-1 receptor agonism-based therapies in end-stage renal disease: A systematic review and meta-analysis.

Article A Peer reviewed Meta-analysis or large trial

Key takeaways

This review combined the results of many studies on GLP-1 drugs in people whose kidneys have failed and who need dialysis. Pulling the studies together, it found these drugs were both safe and helpful for this group. Because it pools many studies rather than one, this is among the stronger kinds of evidence, though it depends on the quality of the studies it included.

Who did this work

Dutta D · Jena S · Mahajan K · Kamrul-Hasan ABM · Bhattacharya S · Mohindra R

Source

Article · PubMed, the drug frontier · 2026 Aug 4
https://pubmed.ncbi.nlm.nih.gov/42551699/