← brief for 2026-08-12 · Slowing decline

Efficacy and Safety of Sodium-Glucose Cotransporter 2 Inhibitors in the Very Elderly with Chronic Kidney Disease: a Retrospective Cohort Study Using Real-World Data

Preprint C Not peer reviewed Observational

Key takeaways

This used real-world records to study SGLT2 blockers, a diabetes drug that also protects kidneys, in people 80 and older with kidney disease. Very old people were left out of the big trials, so this fills a gap. It links starting the drug to survival, kidney and heart outcomes, but as a records study it shows a link, not proof. This early report has not been peer-reviewed yet.

Source

Preprint · medRxiv nephrology preprints · 2026-08-12
https://www.medrxiv.org/content/10.64898/2026.08.11.26360158v1?rss=1