← brief for 2026-08-12 · Slowing decline

Is TRPC6 inhibition for FSGS a trick or a treat? — NephJC

Key takeaways

This was an early (phase 2) trial of a new drug, BI 764198, for FSGS, a disease that scars the tiny filters in the kidney and leaks protein into the urine. People were randomly given either the drug or a dummy pill (placebo), and the results were published in a major journal (the Lancet). An early trial like this tests whether a drug is safe and shows promise. It is a first step, not proof that the drug protects kidneys over the long run.

Source

Page · Forager · 2026-08-13
https://www.nephjc.com/news/trcpc6inhibition-fsgs