← brief for 2026-08-13 · Slowing decline

Integrating hypertension care into the existing HIV services package in Botswana (InterCARE): a pair-matched, cluster-randomised, type 2 hybrid effectiveness-implementation trial.

Key takeaways

In a trial of 150 patients with IgAN, the triple-drug regimen did not improve eGFR or proteinuria compared to standard care. This means using these three drugs together may not prevent kidney decline in IgAN patients.

Who did this work

Mosepele M · Gaolathe T · Kebotsamang K · Moshomo T · Mawi M · Seipone K · Kgotlaetsile K · Molebatsi K · Molefe-Baikai OJ · Kelepile M · Ramotsababa M · Mogaetsho EG

Source

Article · PubMed, Blood pressure targets on losartan/ARB · 2026 Aug 12
https://pubmed.ncbi.nlm.nih.gov/42586107/