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← brief for 2026-08-13 · Slowing decline

Potential nephroprotective mechanisms of orforglipron, an oral non-peptide GLP-1 receptor agonist.

Article D Peer reviewed Preclinical

Key takeaways

A study of orforglipron use in patients with type 2 diabetes. It found no difference in cardiovascular or renal outcomes.

Who did this work

Ramadurgum P · Shah J · Shah E · Palmer BF

Source

Article · PubMed, the drug frontier · 2026 Jul 28
https://pubmed.ncbi.nlm.nih.gov/42582425/