← brief for 2026-08-13 · Slowing decline

Scleroderma Renal Crisis in Mixed Connective Tissue Disease.

Key takeaways

A case series of 5 patients with- or associated with: - scleroderma renal crisis (a severe kidney injury from autoimmune disease), and - malignant hypertension. This condition is very rare in patients with mixed connective tissue disease.

Who did this work

Acharya I (Department of Rheumatology, Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire, USA.) · Ibe-Ejiogu O (Department of Internal Medicine, Medstar Union Memorial Hospital, Baltimore, Maryland, USA.) · Pokharel A (Department of Rheumatology, Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire, USA; Department of Hospital Medicine, Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire, USA.) · Burns CM (Department of Rheumatology, Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire, USA.) · Rigby WFC (Department of Rheumatology, Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire, USA.)

Source

Paper · Europe PMC, CKD · 2026-08-06
https://doi.org/10.1016/j.amjmed.2026.07.029