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← brief for 2026-08-14 · Regeneration & devices

Zhenwu decoction modulates sphingolipid metabolism reprogramming in chronic kidney disease via the SphK1/S1P/S1PR2 pathway.

Article D Peer reviewed Preclinical

Key takeaways

In mice with kidney disease, the drug combination improved renal function. This was seen in both male and female mice.

Who did this work

Cao Y · Liao Y · Long Z · Ma J · Jiang H · Zeng Z · Wang S · Su Y · Liang C · Wu J · Zhou Y · Zhou J

Source

Article · PubMed, fibrosis reversal · 2026 Aug 13
https://pubmed.ncbi.nlm.nih.gov/42595067/