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ORIGIN 3 interim-story: atacicept in IgAN — NephJC

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Key takeaways

A kidney journal club discussed ORIGIN 3, a large trial testing the drug atacicept for IgA nephropathy, a disease where the immune system damages the kidneys. The trial is looking at whether the drug lowers protein in the urine, a sign of kidney damage. This is a recap of the 36-week check-in discussion, not the full data, so no firm numbers are shared here.

Source

Page · Forager · 2026-08-13
https://www.nephjc.com/news/2025/11/origin3-proteinuria-jfyt8