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← brief for 2026-08-17 · Regeneration & devices

Erastin-sensitive VDAC2 contributes to time-course peritoneal fibrosis via ferroptosis signaling induction.

Article D Peer reviewed Preclinical

Key takeaways

In the lab, scientists studied why the lining used in peritoneal dialysis gets scarred over time. They found a form of cell death called ferroptosis, driven by a channel named VDAC2, may add to this scarring. This work was done in cells and cell data, not in people yet. It points to a possible target for future treatment.

Who did this work

Wei W · Qiu Y · Luo R · Feng Y

Source

Article · PubMed, fibrosis reversal · 2026 Aug 17
https://pubmed.ncbi.nlm.nih.gov/42606682/