← brief for 2026-08-20 · Slowing decline
Enoxolone Alleviates Renal Fibrosis in Diabetic Kidney Disease by Inhibiting the Smad3-Smad4 Complex.
Key takeaways
A study in mice found that the drug enoxolone reduces kidney scarring (fibrosis) caused by diabetes. This is a preclinical study and not in humans yet.
Who did this work
Lv B · Guo Z · Chen Z · Liu Z · Bao H
Source
Article · PubMed, fibrosis reversal · 2026 Jul 11
https://pubmed.ncbi.nlm.nih.gov/42622050/