← brief for 2026-08-27 · Slowing decline

Alpha-Mangostin in Acute Kidney Injury: Molecular Mechanisms, Regulated Cell Death, and Translational Opportunities.

Article D Peer reviewed Preclinical

Key takeaways

This review describes how oxidative stress and cell death cause acute kidney injury in animals and cells, and how alpha-mangostin (from mangosteen fruit) may block those pathways. No human trials have been done yet, so it is not known if this helps people.

Who did this work

Phongphithakchai A · Pattaranggoon NC · Wongna K · Netphakdee R · Tedasen A · Jansakun C · Klangbud WK · Thanasai J · Kawakami F · Chatatikun M

Source

Article · PubMed, CKD progression and prevention · 2026 Jul 23
https://pubmed.ncbi.nlm.nih.gov/42650179/