← brief for 2026-08-27 · Nutrition & lifestyle

Berberine-Drug Interactions: Mechanisms, Clinical Relevance and Risk Stratification-A Narrative Review.

Article No results yet Peer reviewed

Key takeaways

A review of how berberine, a popular supplement sold as a natural weight-loss aid, interferes with prescription drugs. Older adults often take it without telling their doctor, and the authors warn it is not harmless. The article sorts the interactions into four mechanisms and ranks the risk. It is not kidney-specific and reports no new results, but people with kidney disease usually take several prescriptions, which is exactly the situation where these interactions bite.

Who did this work

Dumitru CN · Marcu T · Dumitru AO · Tudor SS · Ferțu ID · Elisei AM · Goroftei L

Source

Article · PubMed, the drug frontier · 2026 Aug 20
https://pubmed.ncbi.nlm.nih.gov/42653808/