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← brief for 2026-08-27 · Slowing decline

Disease-modifying anti-diabetic drugs (DMADDs): bridging the SIMPLE approach to disease interception.

Article C Peer reviewed Observational

Key takeaways

This review explains how diabetes drugs like SGLT2 inhibitors and GLP-1 agonists help the heart and kidneys beyond lowering sugar, but it does not include new patient data—only summarizes past studies. It shows a link between these drugs and better kidney outcomes, not proof they cause the benefit.

Who did this work

Koca N · Uyar S · Şahintürk Y · Yıldız H · Del Prato S · DeFronzo R

Source

Article · PubMed, the drug frontier · 2026 Aug 26
https://pubmed.ncbi.nlm.nih.gov/42649514/