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← brief for 2026-08-27 · People & money

Integrating the Urea-to-Creatinine Ratio with Clinical Variables to Improve Etiological Discrimination in Acute Kidney Injury

Paper C Peer reviewed Observational

Key takeaways

Sudden kidney injury has many causes, and telling them apart changes the treatment. This study combined a common blood test ratio, urea to creatinine, with other patient details to sort out the likely cause. It is a diagnosis study in records, so it shows the pattern is linked to the cause, not that it works better in practice. It is about spotting the cause of sudden injury, not about slowing long-term kidney disease.

Who did this work

Luca Malatesta (University of Florence) · Marco Allinovi (Azienda Ospedaliero-Universitaria Careggi) · Sofia Brucia (University of Florence) · Mariapia Carafa (University of Florence) · Sara Dal Lago (University of Florence) · Glenda Cancila (Ospedale San Giuseppe) · Alberto Parise (University of Parma) · Chiara Giannini (University of Florence) · Francesco Peyronel (Mario Negri Institute for Pharmacological Research)

Source

Paper · OpenAlex, Kidney disease concept sweep (verified C2778653478) · 2026-08-26
https://doi.org/10.3390/jcm15176604