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Mechanisms of Obesity-Related Kidney Disease: From Adipose Depot Biology to the Chymase-Aldosterone and Ghrelin-Leptin Axes.

Article C Peer reviewed Observational

Key takeaways

This review links extra fat tissue—especially around the belly—to kidney damage through inflammation and hormone changes, but it does not prove that losing fat will fix the kidneys. It shows a connection, not cause-and-effect.

Who did this work

Hsu HC · Shih LJ · Hou YC · Lu KC

Source

Article · PubMed, the drug frontier · 2026 Aug 8
https://pubmed.ncbi.nlm.nih.gov/42650821/