← brief for 2026-08-27 · Slowing decline

Proteinuria and Kidney Function Trajectories in Patients with Advanced CKD: Insights from CRIC and KNOW-CKD Studies.

Article C Peer reviewed Observational

Key takeaways

In 2,727 adults with advanced kidney disease (filtering rate between 15 and 45), higher protein in the urine was linked to faster decline toward kidney failure, but because this is an observational study, it shows a link — not proof that protein causes faster decline.

Who did this work

Park CH · Hong HJ · Kim HW · Park JT · Chang TI · Yoo TH · Park SK · Kim JS · Lee KB · Jeong JC · Oh KH · Anderson AH

Source

Article · PubMed, CKD progression and prevention · 2026 Aug 27
https://pubmed.ncbi.nlm.nih.gov/42658641/