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Redox-Mediated Mitochondrial Dysfunction as a Common Pathogenic Axis in Acute Kidney Injury and Chronic Kidney Disease.

Key takeaways

This is a review article, not a new study, so it reports no results of its own. It pulls together lab research on how the energy-making parts of kidney cells (mitochondria) get damaged by unstable oxygen molecules called free radicals. The authors argue this same damage runs through sudden kidney injury, long-term kidney disease, and diabetes-related kidney disease. It is a map of possible drug targets, not evidence that any treatment works.

Who did this work

Młynarska E · Bojdo K · Hossa K · Lisińska W · Krawiranda K · Krupińska N · Kustosik N · Wieczorek A · Rysz J · Franczyk B

Source

Article · PubMed, CKD progression · 2026 Aug 7
https://pubmed.ncbi.nlm.nih.gov/42650814/