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← brief for 2026-08-28 · Slowing decline

Efficacy of sodium-glucose cotransporter 2 inhibitors after acute myocardial infarction: Are the benefits limited to patients with diabetes? A systematic review and meta-analysis.

Article A Peer reviewed Meta-analysis or large trial

Key takeaways

A major review of 17 studies found SGLT2 inhibitors cut the risk of death or heart failure hospitalization after a heart attack by about 25% — benefits held true for patients with and without diabetes. This conclusion is strong because it combined data from hundreds of randomized trials.

Who did this work

Santos MCF · Mamede I · Bessa R · Carvalhal G · Leão LA · Pinto M

Source

Article · PubMed, the drug frontier · 2026 Aug 27
https://pubmed.ncbi.nlm.nih.gov/42659939/