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Podocyte hypertrophy in segmental sclerotic lesions correlates with poor renal outcomes in PLA₂R-associated membranous nephropathy

Paper C Not peer reviewed Observational

Key takeaways

In people with a specific kidney disease (PLA₂R-associated membranous nephropathy), larger podocytes in certain lesions were linked to worse kidney outcomes, but this observational study shows only a connection — not proof that changing podocyte size would help.

Who did this work

Jiao Luo (Nanfang Hospital) · Yuhui Yan (Nanfang Hospital) · Jianwei Tian (Nanfang Hospital) · Licong Su (Nanfang Hospital) · Guobao Wang (Nanfang Hospital)

Source

Paper · OpenAlex, Kidney disease concept sweep (verified C2778653478) · 2026-08-27
https://doi.org/10.21203/rs.3.rs-10352353/v1