← brief for 2026-08-29 · Slowing decline

Higher eGFRdiff is associated with increased risk of rapid kidney function decline in hypertensive individuals

Key takeaways

In people with high blood pressure, a bigger gap between two blood tests of kidney filtering rate (eGFR) went with faster loss of kidney function later. The two tests measure different substances, creatinine and cystatin C, and they do not always agree. That gap may be a warning sign worth watching. This shows a link, not proof of cause, and the group size and follow-up time were not in the summary available.

Who did this work

Lu Zhang (Shanghai Jiao Tong University) · Lu Zhang (Shanghai Jiao Tong University) · Qian-Qian Wang (Shanghai Jiao Tong University) · Chao-Fei Shen (Shanghai Jiao Tong University) · Le Zhang (Shanghai Jiao Tong University) · Le Zhang (Shanghai Jiao Tong University) · Jun Wu (Shanghai Jiao Tong University)

Source

Paper · OpenAlex, Kidney disease concept sweep (verified C2778653478) · 2026-08-28
https://doi.org/10.1186/s12882-026-05248-7