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Matters arising: effect modification by chronic kidney disease on renal outcomes in septic shock patients undergoing high-MAP targeting: a secondary analysis of the OPTPRESS trial

Paper B Peer reviewed Small trial

Key takeaways

This secondary analysis of a sepsis trial found that targeting higher blood pressure did not improve outcomes for patients with kidney disease. The results were consistent across different-risk groups.

Who did this work

Maajid Mohi Ud Din Malik (Dr. D.Y. Patil Vidyapeeth, Pune) · Rajesh Jayaswal (Chandigarh University)

Source

Paper · OpenAlex, CKD works · 2026-08-14
https://doi.org/10.1186/s40560-026-00903-5