← brief for 2026-08-19 · Slowing decline
Discovery of Aspxanthones A-I with SIRT1 agonist activity from Aspergillus sp. TJ507.
Key takeaways
Nine new xanthones found in fungus TJ507. Two showed modest SIRT1 activation in cell cultures, but effects on kidney health are unknown.
Who did this work
Lan X · Liang D · Tang L · Chen M · Meng D · Huang X · Gao Y · Qi C · Zhang Y
Source
Article · PubMed, CKD progression and prevention · 2026 Aug 13
https://pubmed.ncbi.nlm.nih.gov/42612273/