← brief for 2026-08-26 · Transplant & xeno

Are We Winning at Twinning? Persistent CNI Use in Identical Kidney Transplants.

Key takeaways

An identical twin transplant is the one case where the donated kidney matches the body exactly, so anti-rejection drugs should not be needed. Researchers looked back at transplant records and found doctors still often prescribe calcineurin inhibitors, a class of anti-rejection drug that damages kidneys over years. They then checked whether those drugs actually lowered rejection or helped the transplanted kidney last longer. This is a look back at existing records, so it shows patterns, not proof of cause.

Who did this work

Herrera NS · Wadnerkar S · Cibrik DM

Source

Article · PubMed, CKD progression and prevention · 2026 Aug
https://pubmed.ncbi.nlm.nih.gov/42640087/