← brief for 2026-08-26 · Transplant & xeno

Association of an early postoperative immune frailty index with a 6-month composite of infection and acute rejection in older kidney transplant recipients

Paper C Peer reviewed Observational

Key takeaways

Older people who get a kidney transplant face two opposite risks: infection from anti-rejection drugs, and the body rejecting the new kidney. Researchers built an immune frailty score from blood tests taken soon after surgery and found higher scores went with more infections and rejections over six months. This is an observational study, so it shows a link, not proof of cause. The score is not ready to guide treatment yet.

Who did this work

Rongxin Chen (Second Affiliated Hospital of Guangzhou Medical University) · Luhao Liu (Second Affiliated Hospital of Guangzhou Medical University) · Guanghui Li (Second Affiliated Hospital of Guangzhou Medical University) · Jiali Fang (Second Affiliated Hospital of Guangzhou Medical University) · Jialin Wu (Second Affiliated Hospital of Guangzhou Medical University) · Zebin Guo (Second Affiliated Hospital of Guangzhou Medical University) · Zheng Chen (Second Affiliated Hospital of Guangzhou Medical University)

Source

Paper · OpenAlex, Kidney disease concept sweep (verified C2778653478) · 2026-08-20
https://doi.org/10.1186/s12877-026-08147-6