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Challenges of Biomarker Application in Patients with Cardiorenal Syndrome

Key takeaways

A review of the blood and urine tests doctors use when heart failure and kidney disease happen at the same time, a pairing called cardiorenal syndrome. The authors argue these tests are hard to read in real patients, because failing kidneys change the test numbers themselves. That makes it easy to misjudge how sick the heart is. This is a discussion paper, not a new study, so there are no results.

Who did this work

Elina Khattab (University of Nicosia) · Sotiris Kyriakou (Queen Mary University of London) · Dimitrios Karelas (Hellenic Red Cross) · Maria Ioannou (Limassol General Hospital) · Evangelos Tatsis (Hellenic Red Cross) · Panagiotis Bouzios (Queen Mary University of London) · Andreas Mitsis (Nicosia General Hospital) · Constantinos H. Papadopoulos (Hellenic Red Cross) · Nikolaos P. E. Kadoglou (University of Nicosia)

Source

Paper · OpenAlex, CKD works · 2026-08-20
https://doi.org/10.3390/biomedicines14081864