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Empagliflozin Improves Post-Infarct Heart Failure Through Fibroblast Growth Factor-21 and Ketone Body Oxidation Pathway.

Article D Peer reviewed Preclinical

Key takeaways

In mice that had heart attacks, empagliflozin improved heart function by changing how the body uses fat and ketones—this effect depended on two proteins, but no people were studied.

Who did this work

Dai DF · Martins I · Daneshgar N · Gao M · Rodriguez B · Khan MM · Hinton A Jr · Crawford PA · Grueter C

Source

Article · PubMed, the drug frontier · 2026 Aug 18
https://pubmed.ncbi.nlm.nih.gov/42645205/