← brief for 2026-08-26 · People & money

Familial hypomagnesemia with hypercalciuria and nephrocalcinosis (FHHNC) with ocular involvement due to a novel CLDN19 variant.

Key takeaways

This case report describes a rare genetic disorder causing low magnesium and kidney stones that can lead to kidney failure, but it does not test any treatment or report outcomes for a group of patients.

Who did this work

Alhothali W (Division of Pediatric Ophthalmology, Department of Pediatric Surgery, King Abdullah Specialist Children's Hospital (KASCH), King Abdulaziz Medical City, Ministry of National Guard Health Affairs (MNG-HA), Riyadh, Saudi Arabia.) · Hijazi S (King Abdullah International Medical Research Centre (KAIMRC), Ministry of National Guard Health Affairs, Riyadh, Saudi Arabia.) · Alharbi E (King Abdullah International Medical Research Centre (KAIMRC), Ministry of National Guard Health Affairs, Riyadh, Saudi Arabia.) · Al Fakeeh K (King Abdullah International Medical Research Centre (KAIMRC), Ministry of National Guard Health Affairs, Riyadh, Saudi Arabia.) · Al Qahtani AT (King Abdullah International Medical Research Centre (KAIMRC), Ministry of National Guard Health Affairs, Riyadh, Saudi Arabia.) · Almannai M (King Abdullah International Medical Research Centre (KAIMRC), Ministry of National Guard Health Affairs, Riyadh, Saudi Arabia.) · Al Tuwaijri A (King Abdullah International Medical Research Centre (KAIMRC), Ministry of National Guard Health Affairs, Riyadh, Saudi Arabia.) · Eyaid W (King Abdullah International Medical Research Centre (KAIMRC), Ministry of National Guard Health Affairs, Riyadh, Saudi Arabia.) · Alfreihi S (Division of Pediatric Ophthalmology, Department of Pediatric Surgery, King Abdullah Specialist Children's Hospital (KASCH), King Abdulaziz Medical City, Ministry of National Guard Health Affairs (MNG-HA), Riyadh, Saudi Arabia.)

Source

Paper · Europe PMC, CKD · 2026-08-24
https://doi.org/10.1080/13816810.2026.2720672