← brief for 2026-08-26 · Regeneration & devices

Heterozygous truncating variants in <i>BICC1</i> are a novel cause of autosomal-dominant tubulointerstitial kidney disease

Key takeaways

Scientists found that certain gene changes in the BICC1 gene can cause a rare inherited kidney disease in families, based on lab analysis of DNA from affected people. This was not a study in animals or cells — it looked at human families — but the paper is a preprint and has not yet been peer-reviewed, so it cannot be confirmed. No treatments or trials are mentioned.

Who did this work

Eylath N · Kidd KO · Alyea-Herman P · Meyersiek J · Colombo DA · Rennke HG · Guleserian AJ · Adams VW · Bianchi G · Maillard A · Faguer S · Izzi C

Source

Paper · Europe PMC, CKD · 2026-08-23
https://doi.org/10.64898/2026.08.20.26360556