← brief for 2026-08-26 · Transplant & xeno

HLA-A, -B, and DR Mismatch and Outcomes After Simultaneous Pancreas-Kidney Transplantation in the Modern Era.

Article C Peer reviewed Observational

Key takeaways

In over 1,200 people who received a kidney and pancreas transplant together, more mismatches in immune system markers were linked to higher risk of kidney failure — but this study shows only a link, not proof that mismatches caused the failures.

Who did this work

Sachdeva M · Tingle S · Kourounis G · Malik A · Thompson E · White S · Sheerin NS · Wilson C

Source

Article · PubMed, CKD severity and reversal · 2026 Aug
https://pubmed.ncbi.nlm.nih.gov/42638165/