← brief for 2026-08-26 · People & money

Overcoming Trial Exclusion: A Multicenter Analysis of Hemodialysis Multiple Myeloma Patients Who Underwent BCMA-Directed CAR-T Therapy.

Article C Peer reviewed Observational

Key takeaways

This study looked back at 8 dialysis patients with cancer who received a new immune therapy (CAR-T) and found they survived about as long as other patients in the study, despite being excluded from original trials. Because it was a回顾 (retrospective) look at real cases—not a controlled study—it shows a possible link, not proof that the therapy caused the outcome.

Who did this work

Zolotov E · Mody R · Doucette K · Chappell A · Accolatse-Mati C · Parmar H · Di Palma-Grisi J · Biran N · Phull P · Franz J · Siegel DS · Vesole DH

Source

Article · PubMed, CKD progression · 2026 Aug 13
https://pubmed.ncbi.nlm.nih.gov/42645380/