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Recent advances in PANoptosis research in kidney disease: mechanistic networks, pathological roles, and potential intervention strategies

Key takeaways

A review of PANoptosis, a form of cell death that mixes together several ways a cell can die, in kidney disease. It gathers lab findings on how these cell death pathways may drive kidney damage, and points to places where a drug might block them. The authors ran no experiments and report no results, in animals or in people.

Who did this work

Shifan Yang (Henan University of Traditional Chinese Medicine) · Xun Li (Guangdong Provincial Hospital of Traditional Chinese Medicine) · Chenming Zhang (Guangdong Provincial Hospital of Traditional Chinese Medicine) · Sicheng Ma (Henan University of Traditional Chinese Medicine) · 周瑛达 (Henan University of Traditional Chinese Medicine)

Source

Paper · OpenAlex, CKD works · 2026-08-25
https://doi.org/10.3389/fimmu.2026.1902148