← brief for 2026-08-26 · Regeneration & devices

Remodeling lipid and mitochondrial homeostasis: a novel mechanism by which polydatin attenuates renal tubular senescence in chronic kidney disease.

Article D Peer reviewed Preclinical

Key takeaways

In test tubes and mice, polydatin—a compound from Japanese knotweed—reduced signs of aging in kidney cells by fixing lipid and mitochondrial problems, but no people have been tested yet.

Who did this work

Wang T · Wang H · Guo W · Xu L · Feng L · Feng C · Zhang H · Liu H

Source

Article · PubMed, fibrosis reversal · 2026 Aug 25
https://pubmed.ncbi.nlm.nih.gov/42641190/