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Sex differences in trajectories to cardio-renal and mental health outcomes following the onset of type 2 diabetes: An observational cohort study using multi-state analysis in the UK Clinical Practice Research Datalink.

Article C Peer reviewed Observational

Key takeaways

This study followed UK adults through their health records after they were diagnosed with type 2 diabetes. It tracked who later developed heart disease, kidney failure, depression or anxiety, and asked whether men and women followed different paths to those outcomes. It watched people rather than testing a treatment, so it shows links, not proof of cause. The value is in flagging who may need closer kidney and mental health checks after a diabetes diagnosis.

Who did this work

Eto F · Samuel M · Stow D · Henkin R · Angdembe A · Barnes MR · Finer S · Mathur R

Source

Article · PubMed, CKD progression and prevention · 2026 Aug 25
https://pubmed.ncbi.nlm.nih.gov/42640878/