← brief for 2026-08-26 · Transplant & xeno

Should we ligate haemodialysis fistulas in patients once they have been transplanted successfully: a randomised feasibility study for a parallel randomised controlled trial

Key takeaways

After a successful kidney transplant, the surgically made arm connection used for dialysis, called a fistula, is no longer needed, and doctors disagree about whether to tie it off. This is a small warm-up study testing whether a full randomized trial on that question could actually be run. It measures feasibility, such as whether enough patients agree to join, not whether tying off the fistula helps. It is a preprint and reports no answer to the medical question.

Who did this work

Veena Surendrakumar (University Hospitals Birmingham NHS Foundation Trust) · Subhankar Paul (Cambridge University Hospitals NHS Foundation Trust) · Shaminie Shanmugaranjan · Emma Aitken (Queen Elizabeth University Hospital) · Patrick B. Mark (Queen Elizabeth University Hospital) · Reza Motallebzadeh (Royal Free London NHS Foundation Trust) · James Hunter (University Hospitals Coventry and Warwickshire NHS Trust) · Aimen Amer (Newcastle upon Tyne Hospitals NHS Foundation Trust) · Dominic M. Summers (Cambridge University Hospitals NHS Foundation Trust) · Kirsten L. Rennie (University of Cambridge) · Leila Rooshenas (University of Bristol) · Lucy Wallis (University of Bristol)

Source

Paper · OpenAlex, Kidney disease concept sweep (verified C2778653478) · 2026-08-25
https://doi.org/10.21203/rs.3.rs-10516401/v1