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Improving the Histologic Classification of Advanced Diabetic Nephropathy Based on the Transformative Research in Diabetic Nephropathy (TRIDENT) Findings

Key takeaways

Diabetic kidney disease is the top cause of kidney failure worldwide, and doctors judge how bad it is by looking at a small piece of kidney tissue under a microscope. The scoring system used today does a poor job of predicting what happens next, especially in advanced disease. Researchers used the TRIDENT study to build a better scoring system. This is observational work, so it shows which tissue patterns go with worse outcomes, not what causes them.

Source

Paper · Kidney International · 2026-08-26
https://www.kidney-international.org/article/S0085-2538(26)00716-7/fulltext?rss=yes