← brief for 2026-09-10 · Slowing decline

FGF23 regulates phosphate and vitamin D metabolism during acute kidney injury and recovery.

Key takeaways

When the kidneys are suddenly injured, a hormone called FGF23 shoots up fast. FGF23 controls how the body handles phosphate, a mineral, and vitamin D. Researchers tracked that hormone over time in rats whose kidney blood flow was cut off and then restored, to see how mineral balance shifts during injury and recovery. This was done in rats, not people, so it explains the biology rather than changing any treatment today.

Who did this work

Komaba H · Nakagawa Y · Ito M · Ishioka C · Fajol A · Wada T · Fukagawa M

Source

Article · PubMed, Nutritional supplements and CKD · 2026 Sep 10
https://pubmed.ncbi.nlm.nih.gov/42721953/