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On-Line High-Volume Hemodiafiltration: Current Evidence and Clinical Outcomes.
Key takeaways
This is a review article about a dialysis method called on-line high-volume hemodiafiltration, or OL-HDF. Regular dialysis clears small waste well but leaves behind bigger "middle molecule" toxins that are tied to heart problems and body-wide inflammation. OL-HDF adds a second cleaning process to pull out more of those larger toxins. The authors summarize existing studies rather than reporting a new one, so there are no new results here.
Who did this work
Maduell F · Galcerán I · Cuadrado-Payán E · Broseta JJ
Source
Article · PubMed, CKD nutrition RCTs · 2026 Sep 10
https://pubmed.ncbi.nlm.nih.gov/42721100/