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Celastrol in kidney diseases: From therapeutic duality and toxicity to precision renal targeting

Article D Peer reviewed Preclinical

Key takeaways

This review looks at a plant-based compound called celastrol. It shows how this compound protects kidneys in animal models. It is not tested in people yet. It could lead to new drugs for kidney disease.

Who did this work

Yi-Ning Chen (Zhejiang Chinese Medical University) · Meng-dan Lu (Zhejiang Chinese Medical University) · Ting-jiao Xu (Zhejiang Chinese Medical University) · Yuewen Tang (Zhejiang Chinese Medical University) · Jia-wei Cao (Zhejiang Chinese Medical University) · Feng Wan (Zhejiang Chinese Medical University)

Source

Article · OpenAlex, CKD works · 2026-09-17
https://doi.org/10.4103/apjtb.apjtb_423_26