← brief for 2026-09-17 · Regeneration & devices

Elevated glucose in kidney organoids induces tissue-intrinsic inflammation driving epithelial detachment.

Key takeaways

This study used tiny, lab-grown kidney models called organoids. It showed that high sugar levels cause inflammation and cell damage in these models. This was done in the lab, not in people yet. It helps scientists understand how diabetes hurts the kidneys at a basic level.

Who did this work

Spennati G · Vo N · Regier MC · Ward HH · Das V · Karihaloo A · Freedman BS

Source

Article · PubMed, organoids & devices · 2026 Sep 17
https://pubmed.ncbi.nlm.nih.gov/42753732/